L-fucose

L-fucose


Fucose (Fuc, 6-deoxy L-galactose) has a methyl group at C6 in place of a hydroxyl group and this gives the molecule a greater degree of hydrophobicity than galactose (Collins, 2006). L-fucose is found in fucoidan, a polysaccharide that occurs in the brown seaweeds (Phaeophyceae) (Percival, 1967). Fucose is also a key component in many mammalian N- and O-linked glycans, glycolipids, blood group substances and Lewis antigens (Becker, 2003). In human milk, neutral (fucosylated) oligosaccharides (HMO) contain fucose at the terminal position (e.g. 2’ -fucosyllactose and lactodifucopentaose). They represent 35% to 50% of the total HMO content and many in vitro studies suggest that HMOs directly modulate immune responses, acting either locally on cells of the mucosa-associated lymphoid tissues or systemically to inhibit the expression of inflammatory genes, mainly cytokines (Plaza-Diaz, 2018).

Product Description

Catalogue NumberF836100

Chemical NameL-Fucose

Synonyms6-Deoxy-L-galactose; (-)-Fucose; 6-Deoxy-L-galactose; 6-Desoxygalactose; Fucose; L-(-)-Fucose; L-Galactomethylose;

CAS Number2438-80-4

Molecular FormulaC₆H₁₂O₅

AppearanceWhite to Off-White Solid

Melting Point132-134°C

Molecular Weight164.16

Storage-20°C Freezer

SolubilityMethanol (Slightly, Heated), Water (Slightly)

CategoryBuilding Blocks; Carbohydrates and Oligosaccharides;

ApplicationsL-Fucose was isolated from seaweed.


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